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- $Unique_ID{BRK00044}
- $Pretitle{}
- $Title{Huntington's Disease: its Symptoms and Effects}
- $Subject{Huntington's Choreas genes inherited musculoskeletal Nervous System
- Huntington Disease Huntington Chorea progressive hereditary personality
- changes irrational apathetic manic-depressive schizophrenia walk spastic
- involuntary muscles gene genetic brain dipolar walking muscle}
- $Volume{F-1, M-1}
- $Log{}
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- Copyright (c) 1991-92,1993 Tribune Media Services, Inc.
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- Huntington's Disease: its Symptoms and Effects
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- QUESTION: Can you tell me about Huntington's Disease? Where does it come
- from, and what are its symptoms and effects?
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- ANSWER: It is sometimes called Huntington's Chorea or more precisely,
- progressive hereditary chorea. It is an inherited disease, carried by a
- single dominant gene, which means that if present in the genetic makeup of an
- individual, it will always cause the disease. The tragedy of Huntington's is
- that the disease doesn't begin to manifest itself until middle age (35-50
- years old) when many sufferers have already married and had children. The
- odds are that 1 out of 2 children will also have the disease which strikes men
- and women equally. It begins in an insidious fashion, striking at the mind
- and body. The patient's personality changes, as he/she becomes irrational or
- apathetic, or a manic-depressive or schizophrenia-like illness may develop
- before the beginning of the muscle problems. The patient cannot walk, may
- have difficulty in swallowing, eventually cannot care for themselves as the
- choreic (spastic, involuntary, irregular) movements of the muscles become
- worse. The disease continues to the inevitable end, as there are no cures or
- treatments, and medications can only partially reduce the symptoms. The
- recent discovery of a genetic marker for Huntington's permits physicians to
- offer considered counsel. Members of families in which the gene is present
- are generally advised to avoid child bearing, but should seek genetic
- counseling to aid them in the decision which they alone can make.
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- The material contained here is "FOR INFORMATION ONLY" and should not replace
- the counsel and advice of your personal physician. Promptly consulting your
- doctor is the best path to a quick and successful resolution of any medical
- problem.
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